There is one big problem with turning it OFF: it deletes all launcher configurations for apps inside it. One will have to redo everything after turning it ON each time.
Security patches come directly from Samsung, and there are no issues with those. I don't know specifically about A33, but you should be able to see the security patch on your device under Settings/ Security and Privacy/ Updates. You will get all OEM ...
Google Play System update is stuck several months behind for many devices, including other brands. You will have to wait until they resolve this issue.